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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '179e2a87b445a649b11c1e98913de28f3cc47e23c1e0d4b144b93b18c3cd40dc' 
  AND token = 'bTlhiEmSuwEu15L6lFIVUEDlZEFd3hgwqUDV8nzXJz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}