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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9518ce81ab691123b4eeefc48a6026bcd5e6722dad134cf200048d1c18c6b8da' 
  AND token = 'HM3oth/kxulkb7Q3e9RdxWUF9B5KtJpkVFBJFm4iqyI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}