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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b12c9e9ae3fedc6d18c0fc272a9cb8f0b4004eba1da70fbf54e43fd2bf0a3909' 
  AND token = 'DRMTSEbPuh+bZCB2yagEUHIAehUwIc9Mc5QP799yf6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}