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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '235fdc9b5884e26efb463c56c852e0114117390daec69d304c06f07ab759b1df' 
  AND token = 'e8lvdrbYzHWF3rCJ0xYhEjX0+U+OjQHO6JrAaU1TwEk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}