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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cbb71fe4172dbfc657c9f422ec629804778f4a7fab53e55f890603a148bc23c' 
  AND token = '3FbXksZ5hUGDGpz85skD0xpw1qu9pNvzO2suxnTz+iA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}