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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8660c19b9717ff983c26f6ba45bab9b980a302f37dd2138ac4f5e73907bad8fa' 
  AND token = '4nFj23kgxlbzAMLupPt544N7cjW7MShtbu0gVHfB5FU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}