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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0afcfc935b54d549d29f74e0e3620452674b303c7d129e8e20ae79dda7ccfd7b' 
  AND token = 'rMD+/n6+urHdxeDZQku4cZpI+0+/mZEfahz0XVTzuFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}