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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e39df00fd94499482d6157dfcc9556c0d1d8022d6cc9bcf2cb3f9ed5d38b5a46' 
  AND token = '/hjwcQILUgq8WvEeVaD4xfpp07BSKpPQ48Ci3iDmbEY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}