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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42f40b98baaa91903ad9385c6610ff465812771ed5d1425fee9a8f00addece81' 
  AND token = '3SC9e1vqEOBCK0dIPH27Z8p7OeBPBuk+/d5ZaoFxQxg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}