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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fc24aa3bab5f2f6b7e9f2e7656897d742b615786565be4100f4037f78a961a0' 
  AND token = 'LwErUQJI74urV1tKNqD27XvYq4QenegZ5rpQIDim2I0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}