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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5aaf789cc4ccd237a9c77931480612c78bd9738b44a58eb78f1f1fae5736e57' 
  AND token = 'R2j9yyxXj9U96X2C57w+oBVN6M4LICqOY80hKwrOy9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}