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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ede391c9b33869aa651a1bccc044d8107ec8ffa8a1e4a90c574e4bc3be13fd0c' 
  AND token = '+fF74dyBOUJPYuWAbJwxmJYIoxHZ1IEXT3I87e5EzEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}