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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ce9d5022ec2d7c6a7fdd95ee62daeebe38355b982fcd5e8758e0bcf6ac93f1a' 
  AND token = 'DY5k6WjwJXltp5W1P7hktuNYGa+lZ5NPugjhyOvw+Rc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}