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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee227db44264d9b79c34078e9ffc04b17feccf68ce34ca6a43c679c087c25fba' 
  AND token = 'UEVw0kzL4n+B+/Q51FciyWWS0y0HaZ8e0tUcbh62FAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}