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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54ee0432e5f36c654f3e46d653a50a554cfc363201219574c050f0e0574d895c' 
  AND token = 'eL2sjGi5CVuT3A2yMjIaOR4Cw1/Kdp/hc6Yi49Yi/g8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}