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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f086ed210af7e9f8340486e6b6d18359c572dcbc73d0cd357d72200ee15d6dc' 
  AND token = 'iUJTxE1OTr13WhpVPByVD/fHtbrFqHGIsL6nhnQHuhY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}