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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dae9871845278a699767bb547ff4d2a3d3a3d165c4c3b9952c39d5c2c6d46705' 
  AND token = 'kkmxrXv0pMdqkbnbqM/oqg9B9Qiu6wMd1VGV4CNuu7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}