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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de4af9c58d18863697473a2900d91c5a2d5f0e5fe925f4f73482c70c0a882e39' 
  AND token = 'vFcMvaic5pqhhETsIQwHtG/Nnq8bwBDwm55qsPQZ5hA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}