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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c8c5f0d14c6d5c18181f44ee9545ad4333851cfd771dc8c6ca03b14bd23434a' 
  AND token = '8lwpmrEcMbNq8/lh7lT5LZWZ8DXLj0Lfg9Nss4htIMs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}