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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '078d5382eedea8bcd592b937a54a8a1f9fc752d2997be5118b082f173d5e03be' 
  AND token = 'hDtbhBQLoEJtG8+OaD4X9v2llwU5+0H9Ht6GuFmoFC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}