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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '289330801ad9ab86bd6185bee73f9375a1fe474a409bbb5f49157ae424175373' 
  AND token = 'N473od814z208gGr8TxShFwj65y0b13qv+Qy80oxOkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}