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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc643e1978488ae1136523cef87bf82c4c55b4d222115f29dee2501e86eea744' 
  AND token = '7ODv2ZSoQvloCtf2D7paM6j7btuxpAkZvSTx2uGfI34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}