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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2b748f718b8e5ed7acac3efb5bb09579d1dc0a2bfa8722a8bbae6e744243fbf' 
  AND token = '6B2QmCFx26UBAfceLgCFe16CraQqliC6Me/E8DcWhG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}