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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1a2f346f77a398d129739fa39b08c3ecf421c7a87701ef394c210992e6a8114' 
  AND token = '07UrkMgMeDyHlL38s+k7Xo/994zETCy7c+XwK3e/wWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}