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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a4f226fc84e6b084f45270752f10678ee40ae76b84789be4708c364c6f17473' 
  AND token = 's5f81uvTQB0LNSy2LjC2/KMso9/PyibSaJvgamXUxPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}