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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bdfcefc78487eca974470c3566ea2e14dda2cf96226333e0ffde16b89adeffa3' 
  AND token = 'mwq7D4Q2NZtUL0ETHQS5k3wpoo93GrS6y5PPH2W38iI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}