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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '485cc830b33083b024c64a2c3a4ca9c3871857c0af6f4e1c710d6ae4a0eca0de' 
  AND token = 'KeX/cOutgYY7fIhVA97wkznJyGgbZiOHly5TcQ1nVxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}