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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5d350ffd0210e917ab21e9ac1cc46b6a07e8f29a93403b79e58e9734600fcd1' 
  AND token = '/+H161BLXm3BcB7gepQUhGL8Z7u+8Y8bLK7nu+oGg0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}