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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15777a216040c8f5fcb3161dcf9d37ffa77d596e8f68a3a582481bbd80ef416a' 
  AND token = 'MymadXMDk3YlBDkN7FiR+WZ2GwXI5yfjk1t9ooplqeM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}