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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fa9c86716a0502d8d8b80cdcd30b6d8539e82db90b431237087018ea3df605b' 
  AND token = '11/L+3g2zRT7VYewY6u7C4sVDzTY4r7RNeVfjRNrBLE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}