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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2962ef10e8f7369d8f066fcdf6ec7c0fca667694da44ee12458bc9b56d7b7929' 
  AND token = 'tXDZ+kRI5e2NmW33Zjg9WTWymqOyVr9qCNg9MwXIXo8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}