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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '353aeeac8112ebf7577ee67500b2a27551790a02a933d5a12ee9a5a3548d9c11' 
  AND token = 'lEIdwL84rfJrqU+vSf/koUFTWBtJCatB5cxZzpXkxLQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}