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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa5789368e573b4c604fafaf5ceb1362e3e310e24902f70033f6909bc27caa29' 
  AND token = 'Fdp0+1SCcmSmOe71d5wyHaA87jjA41/IMkNi0oZfMIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}