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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e18f4a7f412c273876bc77aecb939717c31561fc585e381872077160d114ed28' 
  AND token = 'SL3tT+qMln1sISguSOfyiv8lPEzouKLG4SkPpRrODCo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}