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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ab8d4f433803b51a20dd6236ce8434a2aa88780221759d2054a18a7224f16db' 
  AND token = 'agS/ve3+K8MXwDGECeaWuZN2bxIyZvFCFgH9iI90AK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}