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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48771b4d8fc9f44855b77ea43622aa7702ddad17222990fd8588a9142987fa0a' 
  AND token = 'JxWLpwilzbLrsD7izDTFn/iq78Qgli1lK0bW37iFnCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}