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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4750e31788d9828b9096d2bad4fdb038eee67d0d2ed5b86ef5c37989ec14a55' 
  AND token = '1t/X/ii/O/z2vVEhh0HFyUjddi5X1ZeQayQauf4b+Gw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}