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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '437a1c587f18c4e204cc568942fab2b86a42948c7e7ebbb7b1f9e2ab8adf7837' 
  AND token = 'nh+rbLEIQkknJb523r/2MQ3l3SBT52Nhvv5vyqWZBj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}