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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ddb9a0b482436accbdd956f57d43564d3a1dcd3858f73678b207676415f7050' 
  AND token = 'gMtnaKRo6DINY91caILbnF2javDdwFAe/jD8NEl1rnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}