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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '352d1852cd97f6558222a09d141e12041881ee031ed1b27ed3af6808a95e9db3' 
  AND token = 'vguXREQiQ/mPupRNTsv78A3GAuFbivYPk6tJKcrm7xY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}