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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad88d8edc319827245e866d60c4c2deb03a83ae23e6fabac1d608c500c93dc74' 
  AND token = '7tnsacyJ+vgcCli9xBpLpiWoSIX90Q1nAjVhTMQsOcY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}