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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d44bd7686360e7fb092ec9e095821d6dd6bc394d5bc5dd2736c9af209e20bf1' 
  AND token = 'r2fJUO78Aj5MmG4bEOTjnX/u6V6w1xvPRpS2Ku42YFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}