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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '946264eebd328af8ce95914f9b2195d49c655489c2b3868322bf93b29f0cd291' 
  AND token = 'wwYYQ9WJJd/wnEci6uEUecWRrpN0kUPZTe2SX244edg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}