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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c74f4f8e026660af43c2a985ede2bb9943396a010eb65a3e7d16fe9023c60940' 
  AND token = 'OvjMbePQXElnltSE/eilT+PsDpvI0/TXK13FIQzGoQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}