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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f77092878610f1f24aecb0a7a3587704b9c5662e68f41812ed39e18698d3104c' 
  AND token = 'aYf2N0QzpVyeNMG6rgAAYe3jkg/NeQM09xgnkk+lYmo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}