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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0594c7be403c9068a8624b8d2b1e3df743fae6bdec51959fee88680df0aeaa1' 
  AND token = '+G1ZsX971K3tg44bQPl1z7+s+FF3H73uf4w9ESqvRL4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}