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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81dd168206c3f1128a04dc0d22ec9fbac894deaaf6dc0df00eed58a89d2cb06d' 
  AND token = 'blsnMY+wyNvVWUOoqX2G6amV5TNBysWotjGUcrQFutU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}