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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1050b29148e53ab3849112b0428750bda8a077ef25d8b80f55022f325c91d5a2' 
  AND token = '7iO36TLgpq2AFHBiFJFu/Fs0PZDtPwJbvJvtmJhaYCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}