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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdd1f59f7e7827a04949add74a07a0015cdc4c5544983b874050c721825e6ab4' 
  AND token = 'J3PqgEt2w0o/EYI7WyEq0nokyZBtQzPLn8mHnHwDbxY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}