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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09a849c3fa710c82403a38c7f5411fd720fa855abea2d13df0a58e6a0c1e19fb' 
  AND token = 'lEADuNZcL7tgeh08Z8Mh51Je4gkZjIbbOnD7fmJw8qY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}